Moorfields Eye Hospital has contributed to the first international standards for the reporting of clinical trials for artificial intelligence (AI), led by the University of Birmingham and published in Nature Medicine, British Medical Journal and The Lancet Digital Health.
The new guidelines, which experts in AI at Moorfields consulted on, include standards for clinical trials protocols for studies using AI and new reporting guidelines for AI clinical trials. These standards aim to ensure any future evidence around the effectiveness of AI systems is robust and of the highest quality. The use of these guidelines will enable patients, health care professionals and policy-makers to be more confident on whether an AI intervention is safe and effective.
Future clinical trials evaluating an AI intervention will be expected - and often required - to report their publications to these new standards. The guidelines will also help medical professionals, regulators, funders and other decision-makers assess the quality of clinical trials and assess whether the algorithm will provide an overall benefit to the patient. This is a key step towards improving transparency and robustness for clinical trials evaluating AI in health research.
Moorfields is a leader in AI research, with projects such as our Google Health partnership which has the potential to use AI to detect and treat eye conditions. Moorfields is also working to expand the access of AI in health care across the UK.
Moorfields patient, Elaine Manna, from London, was one of a number of patients who helped to develop the new guidelines. She was asked to provide a patient perspective on developing the guidelines after taking part in an AI research at Moorfields.
Elaine commented: “A super-fast algorithm was tested on my eye - diagnosing my condition as well as an expert ophthalmologist or optometrist. This was a development with significant implications for saving sight and reducing waiting times for appointments.
“It’s vital for patients to be equally involved in their healthcare - understanding how decisions are made, being informed and involved in decision making. Helping to develop the guidelines, I went from thinking of myself as someone with a degenerative eye disease to someone who felt empowered.”
Read the guidelines.
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